Comparing Komodo and Pycharm... Pycharm looks more powerful overall!
One place where Komodo seems to have more features is the Replace menu:
1. You can set it to multiline, which is often convenient (see screenshot).
2. You can pick not just one directory (with the option to recurse as in PyCharm), but add several to a list.
3. They also provide a confirm diff which is really useful when doing a complex regex replace.
I'm sure those would be great additions to the program!