Typescript injection with specifying types

Consider I have this Typescript code, with the class DB imported from a library:

class DB {
  run(query:String) {
    // implementation
  }
}

const db:DB = new DB();
db.run("some query code ...");

Is it possible to inject a specific language into the query String (to highlight syntax for "some query code ..."), specifying that the injection should happen only for the "run" method of class DB (imported from a specific package)?
I've seen that JS injections work for TypeScript, however they don't provide a clear API to specify methods of specific classes, and JSElementPattern_Capture jsArgument() is insufficient - there is no method like definedInClass() to specify the type.

Is using types possible while injecting stuff into TypeScript?